Product Overview
G5-7 | T8742 | TargetMol Chemicals
CAS: 939681-36-4
Smiles: CCOC(=O)N1C\C(=C/c2ccccc2F)C(=O)\C(C1)=C\c1ccccc1F
Formula: C22H19F2NO3
Pathway: Angiogenesis|||Apoptosis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells
Target: Apoptosis|||JAK
Receptor: N/A
Bioactivity: JAK2 inhibitor G5-7 is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for glioma study
Molecular Weight: 383, 395
