Product Overview
GDC-0349 | T6510 | TargetMol Chemicals
CAS: 1207360-89-1
Smiles: CCNC(=O)Nc1ccc(cc1)-c1nc2CN(CCc2c(n1)N1CCOC[C@@H]1C)C1COC1
Formula: C24H32N6O3
Pathway: Autophagy|||PI3K/Akt/mTOR signaling
Target: PI3K|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
Molecular Weight: 452, 559
