Product Overview
Gefapixant | T5099 | TargetMol Chemicals
CAS: 1015787-98-0
Smiles: COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O
Formula: C14H19N5O4S
Pathway: Membrane transporter/Ion channel|||Neuroscience
Target: P2X Receptor|||P2 Receptor
Receptor: N/A
Bioactivity: Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
Molecular Weight: 353, 4