Product Overview
Gemcitabine | T0251 | TargetMol Chemicals
CAS: 95058-81-4
Smiles: Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1
Formula: C9H11F2N3O4
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Target: Apoptosis|||Nucleoside Antimetabolite/Analog|||DNA/RNA Synthesis|||Autophagy
Receptor: N/A
Bioactivity: Gemcitabine is a DNA synthesis inhibitor that can inhibit the growth of MIAPaCa2, BxPC3 and Capan2 cells (IC50s: 40/18/12 nM). It can also induce autophagy.
Molecular Weight: 263, 201