Gilteritinib | T4409

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€186.00 - €793.00
SKU:
TMC-T4409
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Product Overview

Gilteritinib | T4409 | TargetMol Chemicals

CAS: 1254053-43-4

Smiles: CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1

Formula: C29H44N8O3

Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors

Target: FLT|||TAM Receptor|||c-Kit

Receptor: N/A

Bioactivity: Gilteritinib is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 Clinicalal trials for acute myeloid leukemia.

Molecular Weight: 552, 724

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