Product Overview
Glasdegib | T6514 | TargetMol Chemicals
CAS: 1095173-27-5
Smiles: CN1CC[C@H](C[C@@H]1c1nc2ccccc2[nH]1)NC(=O)Nc1ccc(cc1)C#N
Formula: C21H22N6O
Pathway: GPCR/G Protein|||Stem Cells
Target: Hedgehog/Smoothened|||Smo
Receptor: N/A
Bioactivity: Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.
Molecular Weight: 374, 448