Product Overview
Glochidiol | TN4140 | TargetMol Chemicals
CAS: 6610-56-6
Smiles: CC(=C)[C@@H]1CC[C@]2(C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)[C@H](O)C[C@@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12
Formula: C30H50O2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Glochidiol exhibits strong inhibitory effects against all three human tumor cell lines (MCF-7, NCI-H-460 and SF-268), it exerts its antiproliferative activity through the involvement of apoptosis. It exhibits a strong inhibitory effect on mouse skin tumor promotion in an in vivo mouse two-stage carcinogenesis test. Glochidiol (IC50 = 290 mol ratio/32 pmol TPA) also shows inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol 13-acetate (TPA).
Molecular Weight: 442, 7
