Product Overview
GLPG2451 | T13705 | TargetMol Chemicals
CAS: 2055015-61-5
Smiles: C[C@H](O)CNC(=O)c1ncc(cc1N)S(=O)(=O)c1ccc(OC(F)(F)F)cc1
Formula: C16H16F3N3O5S
Pathway: Proteases/Proteasome
Target: Cysteine Protease
Receptor: N/A
Bioactivity: GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1 nM).
Molecular Weight: 419, 38