Product Overview
GN44028 | T15396 | TargetMol Chemicals
CAS: 1421448-26-1
Smiles: C1c2ccccc2-c2[nH]nc(Nc3ccc4OCCOc4c3)c12
Formula: C18H15N3O2
Pathway: Angiogenesis|||Chromatin/Epigenetic
Target: HIF
Receptor: N/A
Bioactivity: GN44028 is a hypoxia-inducible factor inhibitor of (HIF)-1 (IC50: 14 nM). GN44028 inhibits hypoxia-induced HIF-1Ī± transcriptional activity. However, It can not be suppressing HIF-1Ī± mRNA expression, HIF-1Ī± protein accumulation, or HIF-1Ī±/HIF-1Ī² heterodimerization.
Molecular Weight: 305, 337