Product Overview
GNE-272 | T15400 | TargetMol Chemicals
CAS: 1936428-93-1
Smiles: CC(=O)N1CCc2c(C1)c(Nc1ccc(cc1F)-c1cnn(C)c1)nn2[C@H]1CCOC1
Formula: C22H25FN6O2
Pathway: Chromatin/Epigenetic
Target: Epigenetic Reader Domain
Receptor: N/A
Bioactivity: GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 Ī¼M for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300.
Molecular Weight: 424, 48
