Product Overview
GNE-493 | T7166 | TargetMol Chemicals
CAS: 1033735-94-2
Smiles: CC(C)(O)c1cc2nc(nc(N3CCOCC3)c2s1)-c1cnc(N)nc1
Formula: C17H20N6O2S
Pathway: PI3K/Akt/mTOR signaling
Target: PI3K|||mTOR
Receptor: N/A
Bioactivity: GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively.
Molecular Weight: 372, 45
