Product Overview
GNE-4997 | T15402 | TargetMol Chemicals
CAS: 1705602-02-3
Smiles: C[C@@]12Cc3[nH]nc(C(=O)Nc4cnn(c4)[C@@H]([C@H]4CCCCS4(=O)=O)c4ccccc4)c3C[C@@H]1C2(F)F
Formula: C25H27F2N5O3S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: GNE-4997 is a potent and selective inhibitor of the interleukin-2-inducible T-cell kinase (Ki: 0.09 nM). The correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects decreases cytotoxicity.
Molecular Weight: 515, 58
