Product Overview
GNE-618 | T15403 | TargetMol Chemicals
CAS: 1362151-42-5
Smiles: FC(F)(F)c1cccc(c1)S(=O)(=O)c1ccc(CNC(=O)c2cnc3[nH]ncc3c2)cc1
Formula: C21H15F3N4O3S
Pathway: Metabolism
Target: NAMPT
Receptor: N/A
Bioactivity: GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM). GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor activity.
Molecular Weight: 460, 43
