Product Overview
GNE-6640 | T5461 | TargetMol Chemicals
CAS: 2009273-67-8
Smiles: CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2[nH]ncc2c1
Formula: C20H18N4O
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination
Target: DUB
Receptor: N/A
Bioactivity: GNE-6640 is a non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 Ī¼M, 0.43 Ī¼M, 20.3 Ī¼M and 0.23 Ī¼M for full length USP7, USP7 catalytic domain, full length USP43 and Ub-MDM2, respectively.
Molecular Weight: 330, 391
