Product Overview
GNF-5 | T1803 | TargetMol Chemicals
CAS: 778277-15-9
Smiles: OCCNC(=O)c1cccc(c1)-c1cc(Nc2ccc(OC(F)(F)F)cc2)ncn1
Formula: C20H17F3N4O3
Pathway: Angiogenesis|||Cytoskeletal Signaling|||Microbiology/Virology|||Tyrosine Kinase/Adaptors
Target: SARS-CoV|||Bcr-Abl
Receptor: N/A
Bioactivity: GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties.
Molecular Weight: 418, 376
