Product Overview
GNF-5837 | T6097 | TargetMol Chemicals
CAS: 1033769-28-6
Smiles: Cc1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1
Formula: C28H21F4N5O2
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: Trk receptor|||PDGFR|||c-Kit
Receptor: N/A
Bioactivity: GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).
Molecular Weight: 535, 503
