Product Overview
GPP78 | T15412 | TargetMol Chemicals
CAS: 1202580-59-3
Smiles: O=C(CCCCCCCn1cc(nn1)-c1cccnc1)Nc1ccccc1-c1ccccc1
Formula: C27H29N5O
Pathway: Autophagy
Target: Autophagy
Receptor: N/A
Bioactivity: GPP78 is a potent inhibitor of Nampt (IC50: 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion). GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells (IC50: 3.8 nM by inducing autophagy). GPP78 has anti-cancer and anti-inflammatory effects.
Molecular Weight: 439, 563