GR231118 | TP2022

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TMC-TP2022
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Product Overview

GR231118 | TP2022 | TargetMol Chemicals

CAS: 158859-98-4

Smiles:

Formula: C110H170N34O24

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: Potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1, receptors respectively). Also a potent and selective NPY Y4 receptor agonist (pEC50 values are 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors respectively). Suppresses food intake in rats in vivo. Also has affinity for neuropeptide FF (NPFF) receptors in vitro (Ki = 43-73 nM).

Molecular Weight: 2352, 77

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