Product Overview
Grazoprevir | T4547 | TargetMol Chemicals
CAS: 1350514-68-9
Smiles: [H][C@@]12C[C@@]1([H])OC(=O)N[C@]([H])(C(=O)N1C[C@@]([H])(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)Oc1nc3cc(OC)ccc3nc1CCCCC2)C(C)(C)C
Formula: C38H50N6O9S
Pathway: Microbiology/Virology|||Proteases/Proteasome
Target: HCV Protease|||SARS-CoV
Receptor: N/A
Bioactivity: MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), 0.15 nM (gt2b), respectively.
Molecular Weight: 766, 91
