Product Overview
GRI977143 | T22812 | TargetMol Chemicals
CAS: 325850-81-5
Smiles: OC(=O)c1ccccc1SCCCN1C(=O)c2cccc3cccc(C1=O)c23
Formula: C22H17NO4S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: GRI 977143 is a selective lysophosphatidic acid 2 receptor non-lipid agonist (EC50 = 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. It also inhibits activation of caspases 3, 7, 8, and 9, Bax translocation, and PARP-1 cleavage.
Molecular Weight: 391, 44