GS-443902 | T5539

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€1,381.00 - €3,948.00
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TMC-T5539
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Product Overview

GS-443902 | T5539 | TargetMol Chemicals

CAS: 1355149-45-9

Smiles: Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N

Formula: C12H16N5O13P3

Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Metabolism|||Microbiology/Virology|||Proteases/Proteasome

Target: Nucleoside Antimetabolite/Analog|||HCV Protease|||SARS-CoV|||DNA/RNA Synthesis|||RSV|||Drug Metabolite

Receptor: N/A

Bioactivity: Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.

Molecular Weight: 531, 203

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