Product Overview
GSA-10 | T22814 | TargetMol Chemicals
CAS: 300833-95-8
Smiles: CCCCCCn1c2ccccc2c(O)c(C(=O)Nc2ccc(cc2)C(=O)OCCC)c1=O
Formula: C26H30N2O5
Pathway: GPCR/G Protein|||Others|||Stem Cells
Target: Others|||Hedgehog/Smoothened
Receptor: N/A
Bioactivity: GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases.
Molecular Weight: 450, 535
