Product Overview
GSK 3008348 hydrochloride | T15583 | TargetMol Chemicals
CAS: 1629249-40-6
Smiles: O=C(O)C[C@@H](C1=CC(N2N=C(C)C=C2C)=CC=C1)CN3C[C@H](CCC(N4)=CC=C5C4=NCCC5)CC3.[x].Cl
Formula: C29H37N5O2.xHCl
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: GSK 3008348 hydrochloride is an integrin αvβ6 antagonist. The affinity (pIC50) for the human - a 6 protein in the Fluorescence Polarisation Assay for GSK 3008348 is 8.1, whereas its affinity in the cell Adhesion Assays was for ανβ6 (pIC50: 8.4); ανβ3 (pIC50: 6); ανβ5 (pIC50: 6.9); ανβ8 (pIC50: 7.7).
Molecular Weight: N/A