Product Overview
GSK-872 | T4074 | TargetMol Chemicals
CAS: 1346546-69-7
Smiles: CC(C)S(=O)(=O)c1ccc2nccc(Nc3ccc4scnc4c3)c2c1
Formula: C19H17N3O2S2
Pathway: Apoptosis|||NF-Κb
Target: RIP kinase
Receptor: N/A
Bioactivity: GSK872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
Molecular Weight: 383, 48
