Product Overview
GSK172981 | T32004 | TargetMol Chemicals
CAS: 1133705-99-3
Smiles: Nc1c(nc2ccccc2c1C(=O)N[C@@H](C1CC1)c1ccccc1)-c1cccc(F)c1
Formula: C26H22FN3O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: GSK172981 is a non-peptide tachykinin NK3 receptor antagonist with a high affinity for the recombinant human (PK (I) value 7.7) and native guinea pig (PK (I) value 7.8) tachykinin NK3 receptor. In vitro, the functional evaluation showed that GSK172981 was a competitive antagonist for the cloned human tachykinin NK(3) receptor (PA (2)=7.2). GSK172981 may be used to treat schizophrenia.
Molecular Weight: 411, 48