GSK1838705A | T3079

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TMC-T3079
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Product Overview

GSK1838705A | T3079 | TargetMol Chemicals

CAS: 1116235-97-2

Smiles: CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12

Formula: C27H29FN8O3

Pathway: Angiogenesis|||MAPK|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors

Target: IGF-1R|||JNK|||S6 Kinase|||ALK

Receptor: N/A

Bioactivity: GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.

Molecular Weight: 532, 58

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