Product Overview
GSK2656157 | T2654 | TargetMol Chemicals
CAS: 1337532-29-2
Smiles: Cc1cccc(CC(=O)N2CCc3c2ccc(-c2cn(C)c4ncnc(N)c24)c3F)n1
Formula: C23H21FN6O
Pathway: Apoptosis|||Autophagy
Target: Apoptosis|||PERK|||Autophagy
Receptor: N/A
Bioactivity: GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay. The selectivty is 500-fold higher against a panel of 300 kinases.
Molecular Weight: 416, 46
