Product Overview
GSK2798745 | T15434 | TargetMol Chemicals
CAS: 1419609-94-1
Smiles: CC(C)(O)c1cnc(cn1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O
Formula: C25H28N6O3
Pathway: Membrane transporter/Ion channel
Target: TRP/TRPV Channel
Receptor: N/A
Bioactivity: GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in research for the treatment of pulmonary edema associated with congestive heart failure.
Molecular Weight: 460, 538