Product Overview
GSK717 | T38361 | TargetMol Chemicals
CAS: 1595278-21-9
Smiles: O=C(NC1=CC=C2C(CCC2)=C1)CN3C4=CC=CC=C4N=C3CCN(C)C(C5=CC=CC=C5)=O
Formula: C28H28N4O2
Pathway: Immunology/Inflammation|||NF-Κb
Target: IL Receptor|||NOD
Receptor: N/A
Bioactivity: GSK717 is a potent and selective inhibitor of nucleotide-binding oligomerization domain 2 (NOD2). GSK717 blocks synergy between NOD2 and TLR2. GSK717 does not affect NOD1, TNFR1 and TLR2-mediated responses.
Molecular Weight: 452, 55