Product Overview
GSK854 | T24115 | TargetMol Chemicals
CAS: 1316059-00-3
Smiles: CCS(=O)(=O)c1ccc(cc1Nc1cc(Nc2ccc(Cl)cn2)ncn1)S(=O)(=O)NC
Formula: C18H19ClN6O4S2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: GSK854 is an effective TNNI3K inhibitor (IC50 < 10 nM). GSK854 shows substantial selectivity against B-Raf (>25-fold) and EGFR (IC50 > 25 μM). It also shows excellent broad-spectrum kinase selectivity with >100-fold selectivity over 96% of kinases tested.
Molecular Weight: 482, 96