Product Overview
GSK864 | T15442 | TargetMol Chemicals
CAS: 1816331-66-4
Smiles: COc1c(C)cc(NC(=O)c2nn(Cc3ccc(F)cc3)c3c2CN(C[C@]3(C)C(N)=O)C(=O)c2ccc[nH]2)cc1C
Formula: C30H31FN6O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).
Molecular Weight: 558, 614
