Product Overview
GSK872 HCl(1346546-69-7 free base) | T4074L | TargetMol Chemicals
CAS: T4074L
Smiles: CC(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=CC4=C(C=C3)SC=N4.Cl
Formula: C19H18ClN3O2S2
Pathway: Apoptosis|||NF-Κb
Target: RIP kinase
Receptor: N/A
Bioactivity: GSK872 HCl is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
Molecular Weight: 419, 94