Product Overview
Gue1654 | T27502 | TargetMol Chemicals
CAS: 397290-30-1
Smiles: CSc1nc2ccc3nc(NC(=O)C(c4ccccc4)c4ccccc4)sc3c2s1
Formula: C23H17N3OS3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Gue1654 is a modulator of oxoeicosanoid receptor 1 (OXE-R). Gue1654 selectively inhibits Gβγ upon activation of the Gαi-βγ heterotrimer by OXE-R. Gue1654 inhibits Gβγ-mediated opening of GIRK1/2 channels in HEK293 cells.
Molecular Weight: 447, 59