Product Overview
GW 5074 | T6525 | TargetMol Chemicals
CAS: 220904-83-6
Smiles: Oc1c(Br)cc(\C=C2/C(=O)Nc3ccc(I)cc23)cc1Br
Formula: C15H8Br2INO2
Pathway: Apoptosis|||MAPK
Target: Apoptosis|||Raf
Receptor: N/A
Bioactivity: GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms.
Molecular Weight: 520, 946
