GW6471 | T8486

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€276.00 - €1,864.00
SKU:
TMC-T8486
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Product Overview

GW6471 | T8486 | TargetMol Chemicals

CAS: 880635-03-0

Smiles: CCC(=O)NC[C@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)N\C(C)=C/C(=O)c1ccc(cc1)C(F)(F)F

Formula: C35H36F3N3O4

Pathway: DNA Damage/DNA Repair|||Metabolism

Target: PPAR

Receptor: N/A

Bioactivity: GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.

Molecular Weight: 619, 685

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