Product Overview
GW6471 | T8486 | TargetMol Chemicals
CAS: 880635-03-0
Smiles: CCC(=O)NC[C@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)N\C(C)=C/C(=O)c1ccc(cc1)C(F)(F)F
Formula: C35H36F3N3O4
Pathway: DNA Damage/DNA Repair|||Metabolism
Target: PPAR
Receptor: N/A
Bioactivity: GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.
Molecular Weight: 619, 685