Product Overview
GW843682X | T15454 | TargetMol Chemicals
CAS: 660868-91-7
Smiles: COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(N)=O)c2cc1OC
Formula: C22H18F3N3O4S
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors
Target: VEGFR|||PLK|||CDK|||PDGFR|||Aurora Kinase
Receptor: N/A
Bioactivity: GW843682X is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).
Molecular Weight: 477, 46