Product Overview
HBX 41108 | T21527 | TargetMol Chemicals
CAS: 924296-39-9
Smiles: Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N
Formula: N/A
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination
Target: DUB|||p53
Receptor: N/A
Bioactivity: HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
Molecular Weight: 266, 642
