Product Overview
Helenalin | T15467 | TargetMol Chemicals
CAS: 6754-13-8
Smiles: [H][C@@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](O)[C@]1([H])C(=C)C(=O)O2
Formula: C15H18O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Helenalin selectively inhibits transcription factor NF-κB by directly targeting p65. Helenalin is an anti-inflammatory sesquiterpene lactone. Helenalin has alkylating activity, targets the cysteine sulfhydryl groups in the p65 subunit of NF-κB, thereby inhibits its DNA binding.
Molecular Weight: 262, 305
