Product Overview
HIF-1 alpha (556-574) TFA (1201633-99-9 free base) | TP1546 | TargetMol Chemicals
CAS: TP1546
Smiles:
Formula: C103H151D2F3N20O36S2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process.
Molecular Weight: 2368, 62
