Product Overview
Hinokiflavone | T4S0181 | TargetMol Chemicals
CAS: 19202-36-9
Smiles: Oc1ccc(cc1)-c1cc(=O)c2c(O)c(Oc3ccc(cc3)-c3cc(=O)c4c(O)cc(O)cc4o3)c(O)cc2o1
Formula: C30H18O10
Pathway: Apoptosis|||Proteases/Proteasome|||Ubiquitination
Target: MMP|||BCL|||E1/E2/E3 Enzyme
Receptor: N/A
Bioactivity: Hinokiflavone is a novel modulator of pre-mRNA splicing activity in vitro and in cellulo. Hinokiflavone blocks splicing of pre-mRNA substrates by inhibiting spliceosome assembly, specifically preventing B complex formation. Hinokiflavone is a SUMO protease inhibitor, inhibiting sentrin-specific protease 1 (SENP1) activity.Hinokiflavone has significant cytotoxicity, it has inhibition of MMP-9.
Molecular Weight: 538, 464