Product Overview
Histatin 5 (TFA)(115966-68-2, free) | TP1446 | TargetMol Chemicals
CAS: TP1446
Smiles: O=C(O)C(F)(F)F.O=C(O)CC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CO)=O)CC1=CNC=N1)=O)C)=O)CCCCN)=O)CCCNC(N)=N)=O)CC2=CNC=N2)=O)CC3=CNC=N3)=O)=O)CC4=CC=C(O)C=C4)=O)CCCCN)=O)CCCNC(N)=N)=O)CCCCN)=O)CC5=CC=CC=C5)=O)CC6=CNC=N6)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC7=CNC=N7)C(N[C@@H](CC8=CNC=N8)C(N[C@@H](CO)C(N[C@@H](CC9=CNC=N9)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@H](C(O)=O)CC%10=CC=C(O)C=C%10)=O)=O)=O)=O)=O)=O)=O)=O
Formula: C135H196N51F3O35
Pathway: Proteases/Proteasome
Target: MMP
Receptor: N/A
Bioactivity: Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
Molecular Weight: 3150, 31
