Product Overview
Homocarbonyltopsentin | T13723 | TargetMol Chemicals
CAS: 172286-77-0
Smiles: Oc1ccc2c(c[nH]c2c1)C(=O)c1ncc([nH]1)C(=O)c1c[nH]c2ccccc12
Formula: C21H14N4O3
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 μM).
Molecular Weight: 370, 368