Product Overview
Homogentisic acid | TCS2070 | TargetMol Chemicals
CAS: 451-13-8
Smiles: OC(=O)Cc1cc(O)ccc1O
Formula: C8H8O4
Pathway: Metabolism|||oxidation-reduction
Target: Antioxidant|||Endogenous Metabolite
Receptor: N/A
Bioactivity: 1. Homogentisic acid shows interesting antioxidant and antiradical activities, and protective effect against thermal-cholesterol degradation, comparable to those of well known antioxidants. 2. Homogentisic acid is the primary precursor of melanin synthesis in Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana. 3. A derivative of homogentisic acid which inhibits Pfnek-1 with an IC(5) around 1.8 muM, this product is moderately active in vitro against a FcB1 P. falciparum strain (IC(5) = 12 muM).
Molecular Weight: 168, 148
