Product Overview
HPI 1 | T22089 | TargetMol Chemicals
CAS: 599150-20-6
Smiles: COCCOC(=O)C1=C(C)NC2=C(C1c1cccc(O)c1)C(=O)CC(C2)c1ccccc1OC
Formula: N/A
Pathway: GPCR/G Protein|||Stem Cells
Target: Hedgehog/Smoothened
Receptor: N/A
Bioactivity: HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation).
Molecular Weight: 463, 522
