Product Overview
HQL-79 | T15503 | TargetMol Chemicals
CAS: 162641-16-9
Smiles: C(CN1CCC(CC1)OC(c1ccccc1)c1ccccc1)Cc1nnn[nH]1
Formula: C22H27N5O
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.
Molecular Weight: 377, 492
