Product Overview
I-CBP 112 | T22846 | TargetMol Chemicals
CAS: T22846
Smiles: COC1=C(OC)C=C(C2=CC(OC[C@H]3CCCN(C)C3)=C(OCCN4C(CC)=O)C(C4)=C2)C=C1
Formula: C27H36N2O5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: A bromodomain is an approximately 110 amino acid protein domain that recognizes monoacetylated lysine residues such as those on the N-terminal tails of histones. Members of the BET family (Bromodomain and extra terminal domain family) have been implicated as targets in human cancer. SGC has developed an inhibitor, I-CBP112, against the CREBBP and EP300 Bromodomains (IC50: 170 nm (CREBBP/EP300)).
Molecular Weight: 468, 59
