Product Overview
Ibutilide Fumarate | T6541 | TargetMol Chemicals
CAS: 122647-32-9
Smiles: OC(=O)\C=C\C(O)=O.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1
Formula: C44H76N4O10S2
Pathway: Membrane transporter/Ion channel|||Metabolism
Target: Calcium Channel|||Sodium Channel
Receptor: N/A
Bioactivity: Ibutilide Fumarate is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval.
Molecular Weight: 885, 23