IC 86621 | T9760

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ā‚¬233.00 - ā‚¬2,181.00
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TMC-T9760
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Product Overview

IC 86621 | T9760 | TargetMol Chemicals

CAS: 404009-40-1

Smiles: O=C(C1=CC=C(C=C1O)N2CCOCC2)C

Formula: C12H15NO3

Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

Target: DNA-PK

Receptor: N/A

Bioactivity: IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 ĀµM for DNA-PK mediated cellular DSB repair.

Molecular Weight: 221, 25

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