Product Overview
Icaritin | T3398 | TargetMol Chemicals
CAS: 118525-40-9
Smiles: COc1ccc(cc1)-c1oc2c(CC=C(C)C)c(O)cc(O)c2c(=O)c1O
Formula: C21H20O6
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells
Target: Apoptosis|||JAK|||STAT|||Autophagy
Receptor: N/A
Bioactivity: Icaritin has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Icaritin has anti-multiple myeloma activity, mainly mediated by inhibiting IL-6/JAK2/STAT3 signaling. Icaritin at low concentration (4 or 8 μMol/L) can promote rat chondrocyte proliferation and inhibit cell apoptosis, while the effect of Icaritin on rat chondrocyte at high concentration was reversed.
Molecular Weight: 368, 385
