Product Overview
ICG001 | T2237 | TargetMol Chemicals
CAS: 847591-62-2
Smiles: Oc1ccc(C[C@@H]2N3[C@H](CN(Cc4cccc5ccccc45)C2=O)N(CCC3=O)C(=O)NCc2ccccc2)cc1
Formula: C33H32N4O4
Pathway: Chromatin/Epigenetic|||Cytoskeletal Signaling|||Stem Cells
Target: Epigenetic Reader Domain|||Wnt/beta-catenin
Receptor: N/A
Bioactivity: ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
Molecular Weight: 548, 63
